Issam A. Awad was born in Beirut, Lebanon September 23, 1956. After completing his secondary studies in Lebanon, he pursued his college education in the United States, receiving the Bachelor or Sciences degree in Biochemistry (Summa Cum Laude) in 1976, Master of Sciences degree in Biochemistry in 1979, and Doctor of Medicine degree in 1980, all from Loma Linda University in California. He graduated First in his medical school class and received the “Student Investigator of the Year” Award, the Griggs Medical Scholarship Award, and was elected to the Alpha Omega Alpha Honor Medical Society. Dr Awad completed his residency training in neurological surgery at the Cleveland Clinic Foundation in 1985, including neurotraumatology training at the Head and Spinal Injury Unit of the Royal Infirmary of Edinburgh in Scotland (1983), and the Crile Traveling Fellowship (1985). He completed a fellowship in Neurovascular Surgery at the Barrow Neurological Institute in Phoenix, Arizona (1985-1986) and was a full-time faculty member at Stanford University School of Medicine (1986-1987). In 1987 he returned to the Cleveland Clinic where he was Head of the Section of Epilepsy Surgery (1988-1992), Head of the Section of Cerebrovascular Surgery and Surgical Director of the Cerebrovascular Center (1990-1993), and Vice-Chairman of the Department of Neurological Surgery (1991-1993). He then moved to Yale University School of Medicine in 1993 as Director of the Neurovascular Surgery Program and the Yale Cerebrovascular Center, in 1994 he was promoted to Professor, and in 1997 he was appointed to the endowed Nixdorff-German Chair in Neurosurgery at Yale. In 2001 Dr Awad joined the University of Colorado School of Medicine as the Ogsbury-Kindt Chair in Neurosurgery and Professor of Neurosurgery, Neurology and Pathology. In 2003, he relocated to Chicago as Professor of Neurosurgery (with tenure) and Vice-chairman for Research and Program Development at Northwestern University, and as Director of Neurovascular Surgery and Neurocritical Care, and co-Director of Stereotactic Radiosurgery at Evanston Hospital (now NorthShore University HealthSystem). In 2010, he was recruited to lead the Neurovascular Surgery Program at the University of Chicago, and is currently a tenured professor in the Biological Sciences Division and the John Harper Seeley Endowed Chair and Professor of Surgery (Neurosurgery), Neurology, the Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior, and the Comprehensive Cancer Center at the University of Chicago Medicine. He also serves as the Director of the Safadi Program of Excellence in Clinical and Translational Neurosciences, and as Senior Faculty Scholar at the Bucksbaum Institute for Clinical Excellence. Dr Awad is active in numerous professional and learned societies. He has served on the Executive Committee of the American Stroke Association, and on the Board of Governors of the American College of Surgeons. He was the Chairman of the Joint Cerebrovascular Section of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, he has directed the Annual Course on Research Update in Neuroscience for Neurosurgeons, and he served as the 51st President of the Congress of Neurological Surgeons. Dr Awad is the Founding past-President of the World Association of Lebanese Neurosurgeons, and the Founding Chairman of Scientific Advisory Board of Angioma Alliance. He has authored over 350 scientific papers and book chapters, and has edited twelve books dealing with cerebrovascular surgery and other aspects of neurological surgery. He has presented over 500 papers and lectures at major meetings and symposia, has been a visiting professor at numerous institutions in the United States and abroad, and is recognized among America’s Best Doctors. His research has been cited more than 41,000 times through 2019, with an H-index of 85. He is the recipient of the Bucy Award for Excellence in Neurosurgical Education, and in 2013, he was awarded the Shield of Distinction and Merit of the Lebanese Order of Physicians. Dr Awad has made numerous scientific contributions including the characterization of subcortical ischemic lesions in the aged, advances in the understanding of the natural history and biologic behavior of vascular malformations of the brain, numerous technical advances in neurovascular and epilepsy surgery, and is a recognized expert in the treatment of neurovascular disease, hemorrhagic stroke and neurosurgical critical care. His research has been funded by the National Institutes of Health since 1998, focusing through 2023 on molecular mechanisms, biomarkers and therapeutic targets in cerebrovascular malformations and minimally invasive techniques for treating hemorrhagic stroke. Awad’s innovations are changing neurosurgical practice throughout the world, and he has trained scores of neurosurgeons, some of whom are leaders of neurosurgical departments in a number of countries. He serves on the United States National Advisory Council for Neurological Disorders and Stroke through 2020, and in 2019 he was elected to the Association of American Physicians.