Gregory J. Zipfel was born in Peoria, IL on February 2, 1969. He received his B.S. degree from the University of Illinois in 1991 and his M.D. degree from Northwestern University in 1995. He subsequently served as a neurosurgery resident at the University of Florida under the mentorship of Drs. Albert Rhoton and Arthur Day and as a cerebrovascular and skull base surgery fellow at the University of Miami under the mentorship of Drs. Roberto Heros and Jacques Morcos. He also completed a post-doctoral research fellowship at Washington University in St. Louis in the world-renowned brain ischemia laboratory of Dr. Dennis Choi.
Following his post-graduate training, he became an Assistant Professor of Neurological Surgery and Neurology at Washington University in St. Louis in 2004. He was promoted to Associate Professor in 2011 and full Professor in 2015 – a position that he currently holds. In addition, he currently serves as Co-Director of the Stroke and Cerebrovascular Center at Barnes-Jewish Hospital / Washington University in St. Louis and is the Director of the Neurological Surgery Residency Program. He is board certified in Neurological Surgery.
Dr. Zipfel focuses his clinical practice on the surgical management of cerebrovascular disease and skull base tumors. He also directs the Cerebrovascular Research Program in the Department of Neurosurgery at Washington University. This program has three primary areas of interest: 1) Examining the pathophysiologic effects of cerebral amyloid angiopathy on cerebral arteriole function and cerebral blood flow and the manner in which these effects contribute to ischemic stroke, intracerebral hemorrhage, and dementia; 2) Exploring the molecular basis and developing novel therapeutics for vasospasm-induced delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage; and 3) Determining and classifying the pathophysiology, natural history, and treatment of dural arteriovenous fistulae. His has been continuously funded by the NIH since 2005 and has also been supported by awards from numerous foundations including the American Heart Association, American Health Assistance Foundation, Brain Aneurysm Foundation, Neurosurgery Research & Education Foundation, Hope Center For Neurological Disorders, and McDonnell Center for Systems Neuroscience. His CV lists over 140 publications – primarily in the areas of cerebrovascular neurosurgery, subarachnoid hemorrhage, and cerebral amyloid angiopathy.
Dr. Zipfel is also a dedicated neurosurgical educator and leader. He serves as the director of the neurological surgery residency at Washington University, has directed several national cerebrovascular surgery courses, served as faculty at a multitude of national and international cerebrovascular surgery courses, serves on the editorial board of the Journal of Neurosurgery, and has served in a variety of leadership positions within the Joint Cerebrovascular Section of the AANS/CNS, the Society of Neurological Surgeons, and the Stroke Council of the American Heart Association.